黎家,男,汉族,1963年4月生,江苏太仓人,博士、教授、博士生导师,现任兰州大学生命科学学院院长,2003年获得俄克拉荷马大学Junior Faculty Award,2008年被教育部聘为“长江学者奖励计画”特聘教授,2009年入选“甘肃省领军人才”。 黎家教授1980年-1984年在兰州大学生物系学习并获得学士学位。1984年-1986年在湖南师範大学生物系任助教。1986年—1989年在中科院植物研究所学习并获得硕士学位。1990年-1991年在中科院植物研究所任助研。1991年-1995年在美国维吉尼亚理工大学获植物生理学博士学位。1997年-2002年在美国密苏里大学哥伦比亚分校从事博士后研究。2002年-2010年在美国俄克拉荷马大学植物与微生物系任助理教授及副教授(终身教职)。通过全球竞聘获任兰州大学生命科学学院院长,于2009年3月全职回国工作。2009年作为团队带头人入选教育部“长江学者和创新团队发展计画”。 黎家教授主要社会兼职有:中国植物生理学会常务理事;中国细胞生物学学会理事;甘肃省植物生理学会理事长;《Food and Energy Security》副主编(Wiley-Blackwell 出版社);《遗传》副主编;《Journal of Integrative Plant Biology》、《Journal of Genetics and Genomics》、《Frontiers In Biology》、《Plant Signaling and Behavior》编委;20多种国际主要学术刊物审稿人;国家基金委细胞生物学二审专家。 黎家教授长期从事植物受体激酶及植物激素油菜素内酯领域的研究,是相关研究领域的国际知名学者。他及他领导的团队分离到多个关键基因,对阐明油菜素内酯的合成、代谢调控及信号转导的分子机理做出了许多开创性的贡献。相关工作在国际重要学术期刊——《Cell》、《Developmental Cell》、《Current Biology》、《Proc. Natl. Acad. Sci. USA》、《Plant Cell》、《Plant Journal》、《Current Opinion in Plant Biology》、《PLoS Genetics》——等上发表。其中黎家教授以第一作者发表于《Cell》的关于发现油菜素内酯共受体激酶BAK1的原创性研究已经成为该研究领域的经典之作,年平均被引用数及被引用总数在所有有关油菜素内酯领域的SCI论文中均名列前茅。
Gou, X. and Li, J.* (2012) Activation Tagging. Methods in Molecular Biology, in press
Gou, X., Yin, H., He, K., Du, J., Yi, J., Xu S., Lin, H., Clouse, S.D., Li, J.* (2012) Genetic Evidence for an Indispensable Role of Somatic Embryogenesis Receptor Kinases in Brassinosteroid Signaling. PLoS Genetics 8(1): e1002452. (Selected by Faculty of 1000 as a "must read" paper)
Li, J.*, Du, J., He, K., and Gou, X. (2012) Cell Death Control by Receptor Kinases in Arabidopsis thaliana. In, F.E. Tax and B. Kemmerling (editors) RECEPTOR-LIKE KINASES IN PLANTS: From Development to Defense. Springer. Volume 13, pp79-91.
Wei, Z-Y and Li, J.* (2011) Receptor kinases mediated brassinosteroid signal transduction in plants. Chinese Bulletin of Life Sciences. 23 (11), 1106-1113.
An, J., Guo, Z., Gou, X., Li, J.* (2011) TCP1 positively regulates the expression of DWF4in Arabidopsis thaliana. Plant Signaling & Behavior, 6: 1117-1118.
Li J.*(2010) Multi-tasking of somatic embryogenesis receptor-like protein kinases.Current Opinion in Plant Biology , 13: 509-514.
Guo, Z., Fujioka, S., Blancaflor, E.B., Miao, S., Gou, X., and Li, J.* (2010) TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana. Plant Cell 22, 1161-1173.
Yang, H., Gou, X., He, K., Xi, D., Du, J., Lin, H., Li, J.* (2010) Arabidopsis BAK1 and BKK1 confer reduced susceptibility to Turnip Crinkle Virus. European Journal of Plant Pathology, 127: 149-156.
Gou, X., He, K., Yang, H., Yuan, T., Lin, H., Clouse, S.D., Li, J.* (2010) Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics 11(1):19 [Epub ahead of print]
Li, D., Wang, L., Wang, M., Xu, Y.Y., Luo, W., Liu, Y.J., Xu, Z.H., Li, J., Chong, K. (2009) Engineering OsBAK1 gene as a molecular tool to improve rice architecture for high yield. Plant Biotechnology Journal 7(8): 791-806.
Wang, X., Kota, U., He, K., Blackburn, K., Li, J. , Goshe, M.B., Huber, S.C., and Clouse, S.D. (2008) Sequential transphosphorylation of the BRI1/BAK1 receptor kinase pair impacts early events in brassinosteroid signaling. Developmental Cell 15, 220-235.
He, K., Gou, X., Powell, R.A., Yang, H., Yuan, T, Guo, Z., and Li, J.* (2008) Receptor-like protein kinases, BAK1 and BKK1, regulate a light-dependent cell-death control pathway. Plant Signaling & Behavior 3 (10), 813-815.
Clouse, S.D., Goshe, M.B., Huber, S.C. and Li, J. (2008) Functional Analysis and Phosphorylation Site Mapping of Leucine-Rich Repeat Receptor-Like Kinases. In, GK Agrawal and R Rakwal (eds) Plant Proteomics: Technologies, Strategies and Applications. John Wiley & Sons, pp 469-484.
Heese, A., Hann, D.R., Gimenez-ibanex, S., Jones, A., He, K., Li, J. , Schroeder, J.I., Peck, S.C., Rathjen, J.P. (2007) The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants. Proc. Natl. Acad. Sci. USA 104, 12217-12222.
He, K., Gou, X., Yuan, T., Lin, H., Asami, T., Yoshida, S., Russell, S.D., Li, J.* (2007) BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell death pathways. Current Biology 17, 1109-1115.
Yuan, T., Fujioka, S., Takatsuto, S., Matsumoto, S., Gou, X.,He, K., Russell, S.D., and Li, J.* (2007) BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana. The Plant Journal51 (2), 220–233. (Selected by Faculty of 1000 as a "must read" paper)
Li, J.* and Gou, X. (2007) Brassinosteroids. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: Chichester
Wang, L., Xu, Y.Y., Li, J. , Powell, R.A., Xu, Z.H., and Chong, K. (2007) Transgenic rice plants ectopically expressing AtBAK1 are semi-dwarfed and hypersensitive to 24-epibrassinolide. Journal of Plant Physiology 164(5), 655-664.
Zhou, A. and Li, J.* (2005) Arabidopsis BRS1 is an active and secreted serine carboxypeptidase. Journal of Biological Chemistry 280 (42), 35554-35561.
Xu, Y.Y., Wang, X.M., Li, J. , Li, J.H., Wu, J.S., Walker, J.C., Xu, Z.H., Chong, K. (2005) Activation of the WUS gene induces ectopic initiation of floral meristems on mature stem surface in Arabidopsis thaliana. Plant Molecular Biology 57 (6), 773-784.
Wang, X.F., Goshe, M. B., Soderblom, E., Phinney, B.S., Kuchar, J., Li, J., Asami, T., Yoshida, S., Huber, S. C., Clouse, S. D. (2005) Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase. The Plant Cell 17(6), 1685-703. (Selected by Faculty of 1000 as a "must read" paper)
Zhou, A., Wang, H., Walker, J.C., and Li, J.* (2004) BRL1, a leucine-rich repeat receptor-like protein kinase, is functionally redundant with BRI1 in regulating Arabidopsis brassinosteroid signaling. The Plant Journal 40, 399-409.
Lee, G., Li, J., Walker, J.C. and Van Doren S.R. (2003) 1H. 13C and 15N resonance assignments of the kinase interacting FHA domain of Arabidopsis thaliana kinase-associated protein phosphatase. J. Biomol NMR 25, 253-254.
Li, J. , Wen, J., Lease, K.A., Doke, J.T., Tax, F.E. and Walker, J.C. (2002) BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling. Cell 110, 213-222. (Selected by Faculty of 1000 as a "must read" paper)
Lease, K.A., Wen, J., Li, J., Doke, J.T., Liscum, E. and Walker, J.C. (2001) A mutant Arabidopsis Heterotrimeric G protein b subunit affects leaf, flower and fruit development. The Plant Cell 13, 2631-2641.
Li, J. , Lease, K.A., Tax, F.E. and Walker, J.C. (2001) BRS1, a serine carboxypeptidase, regulates BRI1 signaling in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 98, 5916-5921.
Li, J. , Lee, G., Van Doren, S.R. and Walker, J.C. (2000) The FHA domain mediates phosphorylation-dependent protein-protein interactions. J. Cell Sci. 113, 4143-4149.
Li, J. , Smith, G.P. and Walker, J.C. (1999) Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain. Proc. Natl. Acad. Sci. USA 96, 7821-7826.
Lin, Q., Li, J., Smith, R.D. and Walker, J.C. (1998) Molecular cloning and chromosomal mapping of type one serine/threonine protein phosphatases in Arabidopsis thaliana.Plant Molecular Biology 37, 471-481.
Li, J. , Hegeman, C.E., Hanlon, W.R., Lacy, G.H., Denbow, D.M. and Grabau, E.A. (1997) Secretion of active recombinant phytase from soybean cell-suspension cultures. Plant Physiology 114, 1103-1111.
Li, J. and Grabau, E.A. (1996) Comparison of somatic embryogenesis and embryo conversion in commercial soybean cultivars. Plant Cell, Tissue Organ Cult. 44, 87-89.