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周永昌(香港乳腺癌专家)

周永昌(香港乳腺癌专家)

周永昌(香港乳腺癌专家)

周永昌,香港乳腺癌专家。

基本介绍

  • 中文名:周永昌
  • 外文名:Louis Wing-Cheong Chow
  • 国籍:中国
  • 性别:男

人物经历

学习经历

1984年5月M.B.B.S(香港大学)。
1999年12月M.S. (香港大学)。
1984年毕业于香港大学医学院,其后到美国纽约斯隆凯特琳纪念癌症中心、耶鲁大学和南加州大学深造。回 港后,任职于香港大学外科学系,并在港大取得外科学临床硕士。

工作简历

1995年到2005年:香港大学乳腺外科主任
1997年到2005年:香港大学副教授。
1999年到2000年:亚洲乳癌协会主席
2000年到2001年:香港大学医学院副院长
2000年:成立港大内首间孙志新中医药实验室,并担任主任一职。
2001年:与现任香港特别行政区食物与卫生局局长高永文医生等人创立香港中西医结合会
2001年到2005年:香港东华医院外科部-洪祖杭乳腺中心主任
2003年:邀请世界各地专家在香港创立“癌转译研究组织(00TR)”,担任行政总监,主要致力于乳腺癌分子治疗方法、乳腺癌抗药性的机制、化学、内分泌和重要的预防方法之研究。至今,癌转译研究组织(OOTR)仍然不断的在乳腺癌治疗手段与新药的使用上开拓非常前沿的临床试验和转化研究。
2005年:周永昌教授成立仁康医疗乳腺综合诊治中心(UNIMED)。仁康拥有多位经验丰富的医护专才,并累积多年乳腺疾病治理经验,配合先进设备,为病人提供更全面的专业服务。医护团队方面包括:妇科、内外专科、整形外科、物理治疗及科研部门,设有数码乳房造影检查、立体定位组织抽取检查及骨质密度测试等。仁康医疗无复能针对个别病况以进行药物及术前治疗,提供全面的专业谘询及治疗后的富康跟进服务,不论生理或心理上都可得到周全的照顾。
职称
癌转译研究组织(OOTR)执行总监
周永昌
香港仁康医疗乳腺综合诊治中心医务总监
香港圣德肋撒医院乳腺诊断治疗中心总监
日本东北大学名誉教授
澳门科技大学特聘教授
澳门镜湖医院顾问医生
第三军医大学西南医院客座教授
宁夏医科大学名誉教授
江西南昌三院客座教授
前任香港医学专科学院名誉教授、亚洲乳癌协会主席、香港大学李嘉诚医学院名誉临床教授

主要贡献

周永昌教授在担任香港大学医疗中心乳腺外科主任和香港华东医院外科部-洪祖杭乳腺中心主任其间,成功引进乳癌微创检查和切除技术,用于治疗两院的乳腺癌病人;他还把前哨淋巴结组织活检技术引入香港医疗界,用作诊断乳腺癌在体内转移的情况;同时,他首次把该技术转移到猪身体上,用作教导香港各大医院的主任级医生,成功开办两次学习班,为前哨淋巴结组织活检技术用于香港乳腺癌病人奠定了坚实的基础。另外, 他还把人类乳腺叶状囊肉瘤植入裸鼠体内,并成功分离和培养出细胞株。
周永昌教授在担任香港大学医学院副院长期间,与学校同仁把美国哈弗大学的“问题导向学习”(Problem-based learning)的方法经改良后套用于港大医学院,使得医学院学生更能灵活学习艰涩的医学知识,至今香港大学全部都採用此方法教学。
除了在临床及教学上的工作,他还曾担任外科学系的教育和训练中心副主任,并出任多项外科院士考试和博士生的考官。
由于卓越的研究经验,他的研究项目获得香港大学和香港政府的多项研究经费,并获聘于数个国际临床研究中心的首席研究员。发表学术论为140余篇。
2010年之后文章发表
The Breast Cancer Working Group presentation was divided into three sections: the epidemiology, pathology and treatment of breast cancer
Toi M, Ohashi Y, Seow A, Moriya T, Tse G, Sasano H, Park BW, Chow LW, Laudico AV, Yip CH, Ueno E, Ishiguro H, Bando H. Jpn J Clin Oncol. 2010 Sep;40 Suppl 1:i13-18...[10-12-31]
国际乳腺癌临床研究现状及展望
叶润燊, 周永昌. 2010第六届全国乳腺癌重庆论坛论文集, pages 5-9...[10-12-31]
Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis
Loo WT, Jin L, Cheung MN, Wang M, Chow LW. J Trans Med. 2010; Nov 4;8:110 ...[10-11-4]
Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer
Giladi N , Kazanov D, Shpitz B, Aroch I, Kraus S and Arber N. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S117-124...[10-4-30]
Pharmacogenetics in breast cancer: focus on hormone therapy, taxanes, trastuzumab and bevacizumab
Longo R , D'Andrea M, Sarmiento R and Gasparini G. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S41-50...[10-4-30]
Combination of radiological and biochemical methods to assess bone mineral density of mandible in fully edentulous patients after chemotherapy: a 5-year prospective study
Loo WTY , Jin LJ, Cheung MNB, Chow LWC, Wang M. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S109-S115...[10-4-30]
Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
Loo WTY , Jin LJ, Chow LWC, Cheung MNB, Wang M. Expert Opin Investig Drugs. 2010;19 Suppl 1: S91-100...[10-4-30]
Evolution of endocrine adjuvant therapy for early breast cancer
Per Eystein Lønning. Expert Opin Investig Drugs. 2010;19 Suppl 1: S19-30...[10-4-30]
Gene expression profiles as an additional tool to conventional predictive factors to assist in management of early endocrine responsive breast cancer
Chow LWC. Expert Opin Investig Drugs. 2010;19 Suppl 1: S13-S17....[10-4-30]
Combat against cancer with science and medicine
Chow LWC and Toi M. Expert Opin Investig Drugs. 2010;19 Suppl 1: S3-4....[10-4-30]
Evaluation of the psychological and biological changes of patients diagnosed with benign and malignant breast tumor
Bai LJ, Liu Q, Wang M, Loo WT, Cheng RW, Chow LW, Cheung MN, Wei KY, Yip AY, Ng EL. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9936 ...[13-1-9]
Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis
Xu C, Zhao J, Loo WT, Hao L, Wang M, Cheung MN, Dou Y, Yip AY, Ng EL, Chow LW, Liu Q. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9937 ...[13-1-9]
The clinical trials of the Organisation for Oncology and Translational Research (OOTR)
Chow LW, Toi M. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10371 ...[13-1-9]
Prevention of oncological diseases: primary and secondary prevention
Chow LW, Yip AY, Ng EL. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10370 ...[13-1-9]
Methods of early detection – Would clinical breast examination and breast ultrasonography a good alternative to mammography?
Adrian Y.S. Yip, W.P. Chu, Louis W.C. Chow, Wings T.Y. Loo, Eleanor Y.Y. Ong, Wincy Chan. Chin J Breast Dis (Electronic Edition), December 2011, Vol.5, No.6, Pages 646-659...[11-12-31]
Selected Special Lectures of OOTR 7th Annual Conference, 2011
This page is supported by an educational grant from GSK...[11-12-14]
Year in review in Asia - The major Asian trials published in 2011 on Breast Cancer
Louis W.C. Chow, Adrian Y.S. Yip, Wai-pui Chu, Eleanor Y.Y. Ong. The Journal of Japan Society of Clinical Oncology, Volume 46, Number 3, 13 Sep 2011, Pages 1176-1181...[11-10-27]
Translational research to realize the full potential of novel agents - an opportunity for vinflunine?
Yip AYS, Ong EYY, Chow LWC. Expert Opinion on Drug Safety. 2011 Sep 30 online...[11-9-30]
乳腺癌个体化新辅助治疗及辅助手段的套用
周 永昌,鲁庆荣,叶润燊. 中国临床肿瘤学进展2011 (The 14th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book, Sep 2011, Article 37)...[11-9-19]
Racial differences in acute toxicities of neoadjuvant or adjuvant chemotherapy in patients with early-stage breast cancer
Han HS, Reis IM, Zhao W, Kuroi K, Toi M, Suzuki E, Syme R, Chow LWC, Yip AYS, Glück S. Eur J Cancer. 2011 Jul 7...[11-7-7]
Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: Sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial
Louis W.C. Chow, Adrian Y.S. Yip, W.P. Chu, Wings T.Y. Loo, and Masakazu Toi. The Journal of Steroid Biochemistry and Molecular Biology, Volume 125, Issues 1-2, May 2011, Pages 112-119...[11-5-1]
Application of biomarkers in sentinel lymph node biopsy for the management of breast cancer
Qing Liu,Wings Tjing Yung Loo,Adrian Yun San Yip,Louis Wing Cheong Chow,Elizabeth Lam Yan Ng,Mary Ngan Bing Cheung. Chin J Breast Dis( Electronic Edition),December 2012,Vol. 6,No. 6...[12-12-31]
Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference
Toi M, Benson JR, Winer EP, Forbes JF, von Minckwitz G, Golshan M, Robertson JF, Sasano H, Cole BF, Chow LW, Pegram MD, Han W, Huang CS, Ikeda T, Kanao S, Lee ES, Noguchi S, Ohno S, Partridge AH, Rouzier R, Tozaki M, Sugie T, Yamauchi A, Inamoto T. Breast Cancer Res Treat. 2012 Nov 11 ...[12-11-16]
具抗药性乳腺癌病人的组合性用药治疗方案及其疗效和监察的探讨
Louis W.C. CHOW, Adrian Y.S. YIP, Qing LIU, Wings T.Y. LOO. The 15th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book中国临床肿瘤学进展2012, pages 240-242 ...[12-9-20]
国际乳腺癌临床研究现状及展望
周永昌,鲁庆荣. 实用乳腺病学, pages 5-24...[12-9-1]
LMTK3 is implicated in endocrine resistance via multiple signaling pathways
Stebbing J, Filipovic A, Lit LC, Blighe K, Grothey A, Xu Y, Miki Y, Chow LW, Coombes RC, Sasano H, Shaw JA, Giamas G. Oncogene. 2012 Aug 6. doi: 10.1038/onc.2012.343. ...[12-8-6]
New therapies in HER2-positive breast cancer: A major step towards a cure of the disease?
Awada A, Bozovic-Spasojevic I, Chow L. Cancer Treat Rev. 2012Aug; 38(5): 494-504...[12-8-1]
Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique
Takada M, Sugimoto M, Ohno S, Kuroi S, Sato N, Bando H, Masuda N, Iwata H, Kondo M, Ssano H, Chow LW, Inamoto T, Naito Y, Tomita M, Toi M. Breast Cancer Res Treat. Jun 2012...[12-6-12]
Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1
Yukiko Shibahara,Yasuhiro Miki,Yoshiaki Onodera,Shuko Hata,Monica SM Chan,Christopher CP Yiu,Tjing Y Loo,Yasuhiro Nakamura,Jun-ichi Akahira,Takanori Ishida,Keiko Abe,Hisashi Hirakawa,Louis WC Chow,Takashi Suzuki,Noriaki Ouchi,Hironobu Sasano. The Journal of Pathology, 30 Apr 2012...[12-4-30]
Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis
ZhiYu Wang, Wings TY Loo, Neng Wang, Louis WC Chow, Dongmei Wang, Feng Han, Xiao Zheng, Jian-Ping Chen. Expert Opinion on Therapeutic Targets, March 2012, Vol. 16, No. S1, Pages S79-S89...[12-3-30]
Understanding Intratumor Heterogeneity
Louis Wing-cheong Chow. The 16th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book中国临床肿瘤学进展2013, pages 505-508...[13-9-26]
Estrogen-receptor antagonist in a premenopausal patient with metastatic breast cancer
Chi-Kei Lam, Louis Wing-cheong Chow. Oncology Tribune, May-Jun 2013, P.15-17...[13-6-30]
Status of oral ulcerative mucositis and biomarkers to monitor posttraumatic stress disorder effects in breast cancer patients
Loo WT, Liu Q, Yip MC, Wang M, Chow LW, Cheung MN, Yip AY, Ng EL. Int J Biol Markers2013 Jun 28;28(2):e168-73...[13-6-28]
New developments in breast cancer prognosis: molecular 
predictors of treatment response and survival
Foo EM, Boost MV, Wong AS,Loo WT,Chow LW, Chow CY. Int J Biol Markers2013 Jun 28;28(2):e131-40...[13-6-28]
Association of cytokines, high sensitive C-reactive protein, VEGF and beta-defensin-1 gene polymorphisms and their protein expressions with chronic periodontitis in the Chinese population
Tian Y, Li JL, Hao L, Yue Y, Wang M, Loo WT, Cheung MN,Chow LW, Liu Q, Yip AY, Ng EL, Chow CY, Chow2 CY. Int J Biol Markers 2013 Apr 23;28(1):e100-e107...[13-4-23]
Application of interleukin-1 genes and proteins to monitor the status of chronic periodontitis
Hao L, Li JL, Yue Y, Tian Y, Wang M, Loo WT, Cheung MN,Chow LW, Liu Q, Yip AY, Ng EL. Int J Biol Markers 2013 Apr 23;28(1):e92-9...[13-4-23]
Acceptable cardiac safety profile of neoadjuvant 5-fluorouracil, epirubicin, cyclophosphamide and celecoxib (FEC-C) for breast cancer: a subanalysis of biomarkers for cardiac injury
Chow LW, Loo WT, Yip AY, Ng EL. Int J Biol Markers2013 Apr 23;28(1):e92-9...[13-4-23]
Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study
Chow LW, Tung SY, Ng TY, Im SA, Lee MH, Yip AY, Toi M, Glück S. Expert Opin Investig Drugs. 2013 Mar;22(3):299-307 ...[13-3-1]
Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Antonio C. Wolff, Ann A. Lazar, Igor Bondarenko, August M. Garin, Stephen Brincat, Louis Chow, Yan Sun, Zora Neskovic-Konstantinovic, Rodrigo C. Guimaraes, Pierre Fumoleau, Arlene Chan, Soulef Hachemi, Andrew Strahs, Maria Cincotta, Anna Berkenblit, Mizue Krygowski, Lih Lisa Kang, Laurence Moore, Daniel F. Hayes. J Clin Oncol. 2013 Jan 10;31(2):195-202. doi: 10.1200/JCO.2011.38.3331 ...[13-1-13]
Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients - an immunohistochemical study of cd8+ and foxp3+ using double immunostaining with correlation to the pat
Chan MS, Wang L, Felizola SJ, Ueno T, Toi M, Loo W, Chow LW, Suzuki T, Sasano H. Int J Biol Markers. 2012 Dec 19:0. doi: 10.5301/JBM.2012.10439 ...[13-1-10]
Evaluation of the psychological and biological changes of patients diagnosed with benign and malignant breast tumor
Bai LJ, Liu Q, Wang M, Loo WT, Cheng RW, Chow LW, Cheung MN, Wei KY, Yip AY, Ng EL. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9936 ...[13-1-9]
Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis
Xu C, Zhao J, Loo WT, Hao L, Wang M, Cheung MN, Dou Y, Yip AY, Ng EL, Chow LW, Liu Q. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9937 ...[13-1-9]
The clinical trials of the Organisation for Oncology and Translational Research (OOTR)
Chow LW, Toi M. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10371 ...[13-1-9]
Prevention of oncological diseases: primary and secondary prevention
Chow LW, Yip AY, Ng EL. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10370 ...[13-1-9]

获奖记录

2012年,他获得中华医学会乳腺癌专业委员会颁发的“金显宅乳腺癌研究纪念奖”,为港澳地区目前唯一获得此荣誉的专家。

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